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Mutation Information
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Mutation Site
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T215A |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Viral Reference
|
HXB2
|
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Relevant Drug
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NRTIs |
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Country
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China |
Literature Information
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PubMed PMID
|
33668946
|
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Disease
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HIV infection/AIDS
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Published Year
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2021 |
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Journal
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Pathogens (Basel, Switzerland) |
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Title
|
HIV Drug Resistance Mutations Detection by Next-Generation Sequencing during Antiretroviral Therapy Interruption in China. |
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Author
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Li M,Liang S,Zhou C,Chen M,Liang S,Liu C,Zuo Z,Liu L,Feng Y,Song C,Xing H,Ruan Y,Shao Y,Liao L |
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Evidence
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However, some minority DRMs at frequencies of 1%-5% disappeared, including N83D with PI-related, K70E, T215A, and K219E with NRTI-related and K101E, Y181C, H221Y and K238T with NNRTI-related, while others emerged, such as NNRTI-related V106A in patient GX088 at a frequency of 8.7%, and L23I, I47V and I84V with PI-related, D67N and F77L with NRTI-related and L100V and F227L with NNRTI-related, which appeared at frequencies of 1%-5% (Figure 3).
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HIV Mutation Detail Information