HIV Mutation Detail Information

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Mutation Information
Mutation Site T215A
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Viral Reference HXB2
Relevant Drug NRTIs
Country China
Literature Information
PubMed PMID 33668946
Disease HIV infection/AIDS
Published Year 2021
Journal Pathogens (Basel, Switzerland)
Title HIV Drug Resistance Mutations Detection by Next-Generation Sequencing during Antiretroviral Therapy Interruption in China.
Author Li M,Liang S,Zhou C,Chen M,Liang S,Liu C,Zuo Z,Liu L,Feng Y,Song C,Xing H,Ruan Y,Shao Y,Liao L
Evidence However, some minority DRMs at frequencies of 1%-5% disappeared, including N83D with PI-related, K70E, T215A, and K219E with NRTI-related and K101E, Y181C, H221Y and K238T with NNRTI-related, while others emerged, such as NNRTI-related V106A in patient GX088 at a frequency of 8.7%, and L23I, I47V and I84V with PI-related, D67N and F77L with NRTI-related and L100V and F227L with NNRTI-related, which appeared at frequencies of 1%-5% (Figure 3).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation