Mutation Information
Mutation Site
|
T1961C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
C |
Nucleotide_Mutation
|
S21Q |
Country
|
Japan |
Literature Information
PubMed PMID
|
33959934
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2021 |
Journal
|
Clinical journal of gastroenterology |
Title
|
Spontaneous reactivation of hepatitis B virus with a frameshift mutation in the precore region in an elderly hepatitis B virus carrier with lifestyle-related diseases. |
Author
|
Takakusagi S,Takagi H,Yokoyama Y,Kizawa K,Marubashi K,Kosone T,Nagashima S,Takahashi M,Murata K,Okamoto H |
Evidence
|
Her HBV genome was typed as subgenotype B1 and possessed a frameshift mutation due to an insertion of T after nucleotide (nt) 1817 and G to A mutations at nt 1896 and nt 1899 (G1896A/G1899A) in the precore region as well as serine to glutamine substitution of amino acid 21 in the core protein
|
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