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Mutation Information
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Mutation Site
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T1858C |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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PreC |
Literature Information
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PubMed PMID
|
21860069
|
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Published Year
|
2011 |
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Journal
|
Antiviral chemistry & chemotherapy |
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Title
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The YMDD and rtA194T mutations result in decreased replication capacity in wild-type HBV as well as in HBV with precore and basal core promoter mutations. |
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Author
|
Zhu Y,Curtis M,Borroto-Esoda K |
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Evidence
|
Towards an understanding of the mechanism by which the PC mutation enhanced virus DNA replication, we created the T1858C mutation (Figure 5A) on the wt genome backbone.
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HBV Mutation Detail Information