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Mutation Information
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Mutation Site
|
T1815C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Country
|
Morocco |
Literature Information
|
PubMed PMID
|
22905181
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression. |
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Author
|
Kitab B,Essaid El Feydi A,Afifi R,Trepo C,Benazzouz M,Essamri W,Zoulim F,Chemin I,Alj HS,Ezzikouri S,Benjelloun S |
|
Evidence
|
Mutations affecting the initiation of translation of pre-C gene (TIM) were found in 7 (3.8%) patients, including A1814C (three ICs), T1815C (one IC), T1815A (one patient with ACH) and C1817T (two ICs). No patients with TIM had concomitant G1896A mutation.
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HBV Mutation Detail Information