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Mutation Information
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Mutation Site
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T1803G |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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BCP |
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Country
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China |
Literature Information
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PubMed PMID
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20846420
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Disease
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HBV associated liver disease
|
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Published Year
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2010 |
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Journal
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BMC infectious diseases |
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Title
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Prevalent HBV point mutations and mutation combinations at BCP/preC region and their association with liver disease progression. |
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Author
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Zhang D,Ma S,Zhang X,Zhao H,Ding H,Zeng C |
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Evidence
|
In univariate binary logistic regression analysis, all the top five high occurrence mutations seemed to relate to ALD, including T1753A/C (OR = 3.2, 95% CI: 1.3-7.9, P = 0.013), A1762T (OR = 3.1, 95% CI: 1.5-6.5, P = 0.003), G1764A (OR = 4.8, 95% CI: 2.1-10.9, P < 0.001), T1803A/G (OR = 5.1, 95% CI: 1-25.4, P = 0.058), and G1896A (OR = 2.4, 95% CI: 1.2-5.0, P = 0.015).
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HBV Mutation Detail Information