Mutation Information
Mutation Site
|
T1802C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
C Promoter |
Combined Mutation
|
bcp.T1803G+bcp.T1802C |
Literature Information
PubMed PMID
|
12210410
|
Disease
|
Occult HBV infection
|
Published Year
|
2002 |
Journal
|
Journal of medical virology |
Title
|
Sequence analysis of pre-S/surface and pre-core/core promoter genes of hepatitis B virus in chronic hepatitis C patients with occult HBV infection. |
Author
|
Kao JH,Chen PJ,Lai MY,Chen DS |
Evidence
|
In addition, a novel core promoter mutant (a dinucleotide substitution: T-to-C at nucleotide 1,802 and T-to-G at nucleotide 1,803, T1802C/T1803G) was found frequently in patients with Occult hepatitis B as compared to sex- and age-matched HBsAg-positive patients (80 vs. 10%, P < 0.001).
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