HPV Mutation Detail Information

> T178G Search Result


Mutation Information
Mutation Site T178G
Mutation Type Nucleotide level
Gene/Protein/Region Type E6
Nucleotide_Mutation D25E
Genotype/Subtype HPV16
Viral Reference AAL96630
Country Korea
Literature Information
PubMed PMID 31727676
Clinical information Yes
Disease Cervical intraepithelial neoplasia
Published Year 2020
Journal Clinical cancer research : an official journal of the American Association for Cancer Research
Title A Phase II, Prospective, Randomized, Multicenter, Open-Label Study of GX-188E, an HPV DNA Vaccine, in Patients with Cervical Intraepithelial Neoplasia 3.
Author Choi YJ,Hur SY,Kim TJ,Hong SR,Lee JK,Cho CH,Park KS,Woo JW,Sung YC,Suh YS,Park JS
Evidence We also found that D25E (T178G), V83L (G350T), and N29S (A647G) were negatively associated with histopathologic regression at V8 (Table 2).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation