Mutation Information
Mutation Site
|
T178G |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
E6 |
Nucleotide_Mutation
|
D25E |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
NC_001526.2
|
Country
|
China |
Literature Information
PubMed PMID
|
30930693
|
Disease
|
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
Published Year
|
2019 |
Journal
|
Cancer cell international |
Title
|
Genetic variations in E6, E7 and the long control region of human papillomavirus type 16 among patients with cervical lesions in Xinjiang, China. |
Author
|
Zhe X,Xin H,Pan Z,Jin F,Zheng W,Li H,Li D,Cao D,Li Y,Zhang C,Fu S,Shao R,Pan Z |
Evidence
|
Fourteen missense mutations were found in the E6 gene; the loci with the highest mutation frequency were T350G (36/75, 48%) and T178G (19/75, 25.3%).
|
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|