Mutation Information
Mutation Site
|
T178G |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
E6 |
Genotype/Subtype
|
HPV16 |
Country
|
Thailand |
Literature Information
PubMed PMID
|
12820481
|
Disease
|
Cervical carcinoma;
Squamous-cell carcinoma
|
Published Year
|
2003 |
Journal
|
Anticancer research |
Title
|
Co-mutation of HPV16 E6 and E7 genes in Thai squamous cervical carcinomas. |
Author
|
Vaeteewoottacharn K,Jearanaikoon P,Ponglikitmongkol M |
Evidence
|
Five groups of E6 variants were identified. A mutation from T to G at nucleotide 178, leading to a change from aspartate to glutamate (D25E), was the most common variation accounting for 70%.
|
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