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Mutation Information
|
Mutation Site
|
T178A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Combined Mutation
|
e6.T178G+e6.T178A |
|
Nucleotide_Mutation
|
D25E |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
21593270
|
|
Disease
|
Cervical carcinoma
|
|
Published Year
|
2011 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
Human papillomavirus type 16 variant analysis of E6, E7, and L1 [corrected] genes and long control region in [corrected] cervical carcinomas in patients in northeast China. |
|
Author
|
Shang Q,Wang Y,Fang Y,Wei L,Chen S,Sun Y,Li B,Zhang F,Gu H |
|
Evidence
|
Nucleotide variation positions of E6 included three silent mutations (G94A, A131C, and T241G) and six missense mutation positions (G176A, T178G/T178A, A276G, T341G, T350G, and A442C), which led to amino acid variations (D25N, D25E, N58S, C80G, L83V, and E115D).
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HPV Mutation Detail Information