Mutation Information
Mutation Site
|
T176C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
S |
Nucleotide_Mutation
|
F8L |
Genotype/Subtype
|
A |
Country
|
France |
Literature Information
PubMed PMID
|
15016847
|
Disease
|
HBV infection
|
Published Year
|
2004 |
Journal
|
Journal of virology |
Title
|
Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene. |
Author
|
Khan N,Guarnieri M,Ahn SH,Li J,Zhou Y,Bang G,Kim KH,Wands JR,Tong S |
Evidence
|
However, 3.4 contained substitutions in the S domain (F8L, G119E, and I208T; Fig. Fig.6)6) owing to the T176C, G510A, and T777C mutations in the viral genome (Table (Table2),2), which might account for the impairment of virion secretion.
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