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Mutation Information
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Mutation Site
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T1768A |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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BCP |
Literature Information
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PubMed PMID
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26063382
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Disease
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Acute on chronic liver failure;
Chronic hepatitis B
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Published Year
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2015 |
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Journal
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Virology journal |
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Title
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Associations between hepatitis B virus basal core promoter/pre-core region mutations and the risk of acute-on-chronic liver failure: a meta-analysis. |
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Author
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Hu F,Bi S,Yan H,Shi Y,Sheng J |
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Evidence
|
Several mutations were significantly correlated with ACLF: T1753V (1.889, 95 % confidence interval (CI) [1.357-2.631]), A1762T (2.696 [2.265-3.207]), G1764A (3.005 [2.077-4.347]), A1762T/G1764A (2.379 [1.519-3.727]), C1766T (1.849 [1.403-2.437]), T1768A (2.440 [1.405-3.494]), A1846T (3.163 [2.157-4.639]), G1896A (2.181 [1.800-2.642]), G1899A (3.569 [2.906-4.385]) and G1896A/A1762T/G1764A (1.575 [1.172-2.116]).
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HBV Mutation Detail Information