|
Mutation Information
|
Mutation Site
|
T1768A |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.T1768A+bcp.C1766T |
|
Genotype/Subtype
|
A;D |
|
Country
|
Morocco |
Literature Information
|
PubMed PMID
|
22905181
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
PloS one |
|
Title
|
Variability in the precore and core promoter regions of HBV strains in Morocco: characterization and impact on liver disease progression. |
|
Author
|
Kitab B,Essaid El Feydi A,Afifi R,Trepo C,Benazzouz M,Essamri W,Zoulim F,Chemin I,Alj HS,Ezzikouri S,Benjelloun S |
|
Evidence
|
CP mutations C1653T, T1753V, A1762T/G1764A, and C1766T/T1768A were associated with higher HBV-DNA level and increased liver disease severity.
|
|
|
HBV Mutation Detail Information