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Mutation Information
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Mutation Site
|
T1768A |
|
Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
BCP |
Literature Information
|
PubMed PMID
|
22061616
|
|
Disease
|
HBV-HCV coinfection
|
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Published Year
|
2012 |
|
Journal
|
Antiviral research |
|
Title
|
Precore/core promoter mutations and hepatitis B virus genotype in hepatitis B and C dually infected patients treated with interferon-based therapy. |
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Author
|
Hung CH,Chen CH,Lu SN,Wang JH,Hu TH,Huang CM,Tsai MC,Lee CM |
|
Evidence
|
A higher serum HBV DNA level (⩾2000 IU/ml) was found to be correlated with C1766T (P < 0.001), T1768A (P = 0.006), G1896A (P = 0.019) and G1899A mutation (P = 0.019), whereas there was no significant association between serum HBV DNA level and A1726C (P = 0.446), A1752TG (P = 0.382), A1762T/G1764A (P = 0.589), C1799G (P = 0.554) and A1846T mutation (P = 0.287).
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HBV Mutation Detail Information