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Mutation Information
|
Mutation Site
|
T1753V |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.T1753V+x.C1653T |
|
Genotype/Subtype
|
C |
|
Country
|
Cambodia |
Literature Information
|
PubMed PMID
|
31434918
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2019 |
|
Journal
|
Scientific reports |
|
Title
|
High possibility of hepatocarcinogenesis in HBV genotype C1 infected Cambodians is indicated by 340 HBV C1 full-genomes analysis from GenBank. |
|
Author
|
Chuon C,Takahashi K,Matsuo J,Katayama K,Yamamoto C,Ko K,Hok S,Nagashima S,Akbar SMF,Tanaka J |
|
Evidence
|
Multiple mutations were confirmed in 24 Cambodian C1 isolates, especially double mutation at A1762T/G1764A in 18 isolates (75.0%), and combination mutation at C1653T and/or T1753V and A1762T/G1764A in 14 isolates (58.3%).
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HBV Mutation Detail Information