|
Mutation Information
|
Mutation Site
|
T1753V |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.T1753V+bcp.G1764A+bcp.A1762T |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
29248936
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2017 |
|
Journal
|
Medical science monitor : international medical journal of experimental and clinical research |
|
Title
|
Patients with Coexistence of Circulating Hepatitis B Surface Antigen and Its Antibody May Have a Strong Predisposition to Virus Reactivation During Immunosuppressive Therapy: A Hypothesis. |
|
Author
|
Chen YL,Mo YQ,Zheng DH,Ma JD,Jing J,Dai L |
|
Evidence
|
DNA sequencing analysis of the HBV genome revealed triple mutations (A1762T, G1764A, and T1753V) in the BCP region, which could further enhance the ability of HBV replication.
|
|
|
HBV Mutation Detail Information