|
Mutation Information
|
Mutation Site
|
T1753V |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
25626648
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2014 |
|
Journal
|
Revista da Sociedade Brasileira de Medicina Tropical |
|
Title
|
Hepatitis B virus genotypes and mutations in the basal core promoter and pre-core/core in chronically infected patients in southern Brazil: a cross-sectional study of HBV genotypes and mutations in chronic carriers. |
|
Author
|
Mello FM,Kuniyoshi AS,Lopes AF,Gomes-Gouvêa MS,Bertolini DA |
|
Evidence
|
Analysis of the BCP and precore/core sequences in the 54 samples showed that the G1896A precore mutation was the most frequent (30/54, 55.6%) followed by the BCP double mutation A1762T/G1764A (22/54, 40.7%), the BCP T1753V mutation (18/54, 33.3%) and the G1899A (14/54, 26%) and G1862T (11/54, 20.4%) precore region mutations.
|
|
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HBV Mutation Detail Information