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Mutation Information
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Mutation Site
|
T1753G |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
BCP |
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Country
|
China |
Literature Information
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PubMed PMID
|
20959817
|
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
|
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Published Year
|
2011 |
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Journal
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The American journal of gastroenterology |
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Title
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Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. |
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Author
|
Yin J,Xie J,Liu S,Zhang H,Han L,Lu W,Shen Q,Xu G,Dong H,Shen J,Zhang J,Han J,Wang L,Liu Y,Wang F,Zhao J,Zhang Q,Ni W,Wang H,Cao G |
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Evidence
|
As compared with those without HCC, C1653T, T1674C / G, G1719T, A1727T, T1753V, C1913A in genotype C and T1753G, A1762T, G1764A, A1846T, and G1896A in both genotypes were signifi cantly associated with HCC (see Supplementary Table 7 )
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HBV Mutation Detail Information