Mutation Information
Mutation Site
|
T1753C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
BCP |
Genotype/Subtype
|
F |
Country
|
Venezuela |
Literature Information
PubMed PMID
|
27382800
|
Disease
|
HBV associated liver disease
|
Published Year
|
2016 |
Journal
|
Investigacion clinica |
Title
|
Genetic diversity of hepatitis B virus and mutations associated to hepatocellular carcinoma in patients from Venezuela, with different stages of liver disease. |
Author
|
Puche ML,Kay-Valero S,Michelli P,Oropeza MD,Loureiro CL,Devesa M,Dagher L,Pujol FH |
Evidence
|
Additionally, mutations were more common in early stages of liver disease in HBV subgenotype F2-infected patients, and a significant association between this subgenotype and the emergence of T 1753C, A1762T, A1762T/G1764A (p=0.04) and C1773T (p=0.001) mutations in chronic patients was found, when compared to the HBV subgenotype F3.
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