Mutation Information
Mutation Site
|
T1753C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
BCP |
Country
|
China |
Literature Information
PubMed PMID
|
27075395
|
Disease
|
Hepatocellular carcinoma
|
Published Year
|
2016 |
Journal
|
Cancer medicine |
Title
|
Hepatitis B virus mutations, expression quantitative trait loci for PTPN12, and their interactions in hepatocellular carcinoma. |
Author
|
Song C,Liu Y,Xu L,Wen J,Jiang D,Chen J,Zhai X,Hu Z,Liu L,Liu J |
Evidence
|
Of those 19 hotspot mutations, C1653T, T1674C/G, A1703G, G1719T, T1727A/G, T1753C, A1762T, G1764A, G1799C, G1899A, G1915A/C, and C1969T were significantly associated with an increased risk of HCC, whereas C1673T, A1726C, C1730G, and A1752G were significantly associated with a reduced risk of HCC, when adjusted for age and gender
|
|
|