|
Mutation Information
|
Mutation Site
|
T1753C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T+bcp.T1753C |
|
Genotype/Subtype
|
C |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
26577140
|
|
Disease
|
Chronic hepatitis B;
Liver cirrhosis
|
|
Published Year
|
2016 |
|
Journal
|
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases |
|
Title
|
Hepatitis B virus basal core promoter/precore mutants and association with liver cirrhosis in children with chronic hepatitis B virus infection. |
|
Author
|
Zhong YW,Di FL,Liu C,Zhang XC,Bi JF,Li YL,Wu SQ,Dong H,Liu LM,He J,Shi YM,Zhang HF,Zhang M |
|
Evidence
|
The C1653T, T1753C, A1762T/G1764A and G1896A mutations had a significantly higher prevalence in patients with LC.
|
|
|
HBV Mutation Detail Information