HBV Mutation Detail Information

> T1753C Search Result

Mutation Information

Mutation Site	T1753C
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	D
Country	India

Literature Information

PubMed PMID	25333524
Disease	Hepatocellular carcinoma; Liver cirrhosis
Published Year	2014
Journal	PloS one
Title	Novel point and combo-mutations in the genome of hepatitis B virus-genotype D: characterization and impact on liver disease progression to hepatocellular carcinoma.
Author	Datta S,Ghosh A,Dasgupta D,Ghosh A,Roychoudhury S,Roy G,Das S,Das K,Gupta S,Basu K,Basu A,Datta S,Chowdhury A,Banerjee S
Evidence	BCP_T1753C, core_T147C, surface_L213I had contributed significantly in the disease progression to HCC (p < 0.05) in HBeAg positive patients whereas precore_T1858C, core_I116L, core_P130Q and preS1_S98T in HBeAg negative patients.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation