HBV Mutation Detail Information

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Mutation Information
Mutation Site T1753C
Mutation Type Nucleotide level
Gene/Protein/Region Type BCP
Viral Reference AY233274.1
Country South Africa
Literature Information
PubMed PMID 23029487
Clinical information Yes
Disease HBV-HIV coinfection
Published Year 2012
Journal PloS one
Title Genotyping and molecular characterization of hepatitis B virus from human immunodeficiency virus-infected individuals in southern Africa.
Author Makondo E,Bell TG,Kramvis A
Evidence Mutations 1762T/1764A known to down-regulate HBeAg expression at the transcriptional level occurred in eight isolates (SHH009, SHH061, SHH148, SHH180, SHH184, SHH221 and SHH264, SHH274), in five cases occurring together with the T1753C.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation