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Mutation Information
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Mutation Site
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T1753C |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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BCP |
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Country
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China |
Literature Information
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PubMed PMID
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20959817
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Disease
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Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
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Published Year
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2011 |
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Journal
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The American journal of gastroenterology |
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Title
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Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. |
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Author
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Yin J,Xie J,Liu S,Zhang H,Han L,Lu W,Shen Q,Xu G,Dong H,Shen J,Zhang J,Han J,Wang L,Liu Y,Wang F,Zhao J,Zhang Q,Ni W,Wang H,Cao G |
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Evidence
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As compared with ASCs and the patients with CHB,C1673T, T1674C, A1703G, A1726C, C1730G, C1799G, A1846T,and C1913A in genotype C and C1653T, G1719T, A1727G,T1753A / C, A1762T, G1764A, C1766T, T1768A, C1773T, and G1896A in both genotypes were signifi cantly associated with LC(see Supplementary Table 6 )
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HBV Mutation Detail Information