Mutation Information
Mutation Site
|
T1753C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
BCP |
Genotype/Subtype
|
C |
Country
|
korea |
Literature Information
PubMed PMID
|
12966541
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2003 |
Journal
|
Journal of medical virology |
Title
|
Evolution of hepatitis B virus sequence from a liver transplant recipient with rapid breakthrough despite hepatitis B immune globulin prophylaxis and lamivudine therapy. |
Author
|
Kim KH,Lee KH,Chang HY,Ahn SH,Tong S,Yoon YJ,Seong BL,Kim SI,Han KH |
Evidence
|
Sequence analysis of full-length viral genome before transplantation revealed many point mutations as compared with a wild-type genotype C sequence, including the T1753G/A1762T/G1764A triple mutation in the basal core promoter and the G1896A nonsense mutation in the precore region.
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