HBV Mutation Detail Information

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Mutation Information
Mutation Site T1753A
Mutation Type Nucleotide level
Gene/Protein/Region Type C Promoter
Combined Mutation c promoter.G1764A+c promoter.A1762T+c promoter.T1753A
Genotype/Subtype C
Viral Reference M12906
Country China
Literature Information
PubMed PMID 19272629
Clinical information Yes
Disease HBV infection
Published Year 2009
Journal Virology
Title Association between genomic heterogeneity of hepatitis B virus and intrauterine infection.
Author Cheng H,Su H,Wang S,Shao Z,Men K,Li M,Li S,Zhang J,Xu J,Zhang H,Yan Y,Xu D
Evidence It was observed that T1753A/A1762T/G1764A triple mutants were present in four mothers (C2, 4, 6 and 8) in group C, but only in one mother-neonate pair (M6 and N6) in groups M and N (χ2 = 4.4216, P = 0.1096, χ2 test) (Table 2).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation