|
Mutation Information
|
Mutation Site
|
T174D |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Rex |
Literature Information
|
PubMed PMID
|
19919707
|
|
Published Year
|
2009 |
|
Journal
|
Retrovirology |
|
Title
|
Phosphorylation regulates human T-cell leukemia virus type 1 Rex function. |
|
Author
|
Kesic M,Doueiri R,Ward M,Semmes OJ,Green PL |
|
Evidence
|
Further mutational analysis of these two residues by converting them to phosphomimetic aspartic acid (S97D and T174D) restored functional activity to wtRex-1 levels, which indicated that phosphorylation plays a positive functional role (Fig. 4A).
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HTLV1 Mutation Detail Information