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Mutation Information
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Mutation Site
|
T1674G |
|
Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
EnhII |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24748463
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2014 |
|
Journal
|
Frontiers of medicine |
|
Title
|
Association of miRNA-122-binding site polymorphism at the interleukin-1 α gene and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk. |
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Author
|
Du Y,Han X,Pu R,Xie J,Zhang Y,Cao G |
|
Evidence
|
The HBV mutations T1674C/G, A1762T/G1764A, G1896A, and T1753V in the EnhII/BCP/PC region and preS deletion,preS2 start codon mutation, C2875A, C76A, and C7A in the preS region, rather than the rs3783553 genotype, were significantly associated with an increased risk of HCC (Table 4).
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HBV Mutation Detail Information