Mutation Information
Mutation Site
|
T1674G |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
EnhII |
Country
|
China |
Literature Information
PubMed PMID
|
24118778
|
Disease
|
Hepatocellular carcinoma
|
Published Year
|
2014 |
Journal
|
Liver international : official journal of the International Association for the Study of the Liver |
Title
|
Association of a potential functional pre-miR-218 polymorphism and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk. |
Author
|
Han Y,Pu R,Han X,Zhao J,Li W,Yin J,Zhang Y,Shen Q,Xie J,Zhang Q,Jiang S,Li J,Zhang H,Wang H,Cao G |
Evidence
|
CONCLUSION: rs11134527 may be a novel genetic risk factor of HCC in HBV-exposed subjects, can facilitate HBV preS deletion generation and predispose the host to the effect of T1674C/G and preS1 start codon mutation in hepatocarcinogenesis.
|
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