HBV Mutation Detail Information

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Mutation Information
Mutation Site T1674G
Mutation Type Nucleotide level
Gene/Protein/Region Type EnhII
Country China
Literature Information
PubMed PMID 24118778
Disease Hepatocellular carcinoma
Published Year 2014
Journal Liver international : official journal of the International Association for the Study of the Liver
Title Association of a potential functional pre-miR-218 polymorphism and its interaction with hepatitis B virus mutations with hepatocellular carcinoma risk.
Author Han Y,Pu R,Han X,Zhao J,Li W,Yin J,Zhang Y,Shen Q,Xie J,Zhang Q,Jiang S,Li J,Zhang H,Wang H,Cao G
Evidence CONCLUSION: rs11134527 may be a novel genetic risk factor of HCC in HBV-exposed subjects, can facilitate HBV preS deletion generation and predispose the host to the effect of T1674C/G and preS1 start codon mutation in hepatocarcinogenesis.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation