|
Mutation Information
|
Mutation Site
|
T1674G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
23386590
|
|
Disease
|
Hepatocellular carcinoma
|
|
Published Year
|
2013 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Interaction of signal transducer and activator of transcription 3 polymorphisms with hepatitis B virus mutations in hepatocellular carcinoma. |
|
Author
|
Xie J,Zhang Y,Zhang Q,Han Y,Yin J,Pu R,Shen Q,Lu W,Du Y,Zhao J,Han X,Zhang H,Cao G |
|
Evidence
|
Rs2293152 GG was significantly associated with high viral load (>=1 x 10(4) copies/mL) (AOR, 1.37; 95%, CI 1.01-1.88) and increased frequencies of T1674C/G (AOR, 1.61; 95% CI, 1.06-2.46) and A1762T/G1764A (AOR, 1.64; 95% CI, 1.14-2.35).
|
|
|
HBV Mutation Detail Information