HBV Mutation Detail Information

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Mutation Information
Mutation Site T1674C
Mutation Type Nucleotide level
Gene/Protein/Region Type C Promoter
Genotype/Subtype C
Country China
Literature Information
PubMed PMID 20959817
Disease Chronic hepatitis B; Liver cirrhosis; Hepatocellular carcinoma
Published Year 2011
Journal The American journal of gastroenterology
Title Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma.
Author Yin J,Xie J,Liu S,Zhang H,Han L,Lu W,Shen Q,Xu G,Dong H,Shen J,Zhang J,Han J,Wang L,Liu Y,Wang F,Zhao J,Zhang Q,Ni W,Wang H,Cao G
Evidence Age, abnormal ALT, HBV DNA (>/=10(4) copies/ml), genotype C, C1653T, T1674C/G, T1753V, and A1762T/G1764A were independently associated with HCC compared with those without HCC.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation