|
Mutation Information
|
Mutation Site
|
T143M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
A |
|
Immune Escape
|
Y |
|
Country
|
Ethiopia |
Literature Information
|
PubMed PMID
|
27354181
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2017 |
|
Journal
|
Antiviral therapy |
|
Title
|
HIV therapy with unknown HBV status is responsible for higher rate of HBV genome variability in Ethiopia. |
|
Author
|
Belyhun Y,Maier M,Liebert UG |
|
Evidence
|
In particular, the 'a' determinant surface gene mutations (sT125S, sA128V, sQ129H/R, sT131I, sC137S, sT143M, sD144D/E, sG145R, sT148P) and the majority of clustered/multiple as well as drug selected immune escape HBsAg mutations were more prevalent in HBV-HIV-coinfected individuals.
|
|
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HBV Mutation Detail Information