HBV Mutation Detail Information

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Mutation Information
Mutation Site T143M
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype B;C
Viral Reference AP011097.1; M54923.1
Country Indonesia
Literature Information
PubMed PMID 21063484
Disease Occult HBV infection
Published Year 2010
Journal Hepatology international
Title Occult hepatitis B in blood donors in Indonesia: altered antigenicity of the hepatitis B virus surface protein.
Author Thedja MD,Roni M,Harahap AR,Siregar NC,Ie SI,Muljono DH
Evidence Seven of the viremic samples had nucleotide substitutions (A521G, A551T, C582T, and A562G) in the S gene, causing amino acid mutations (T123A, M133L, and T143M) in the 'a' determinant of HBsAg that resulted in changes in the predicted antigenicity.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation