Mutation Information
Mutation Site
|
T143M |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Literature Information
PubMed PMID
|
16549970
|
Disease
|
HBV-HIV coinfection
|
Published Year
|
2006 |
Journal
|
AIDS (London, England) |
Title
|
Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy. |
Author
|
Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL |
Evidence
|
These include mutations at sT114R (rtV112I), sP120T (rtT128N), sP120Q (no polymerase change), sK122K/N (rtN131N/H), sQ129R (no polymerase change), sM133I (rtV142I) sF134L (rtS143A), and sT143M (no polymerase change), in which the overlapping polymerase changes are shown in parentheses.
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