|
Mutation Information
|
Mutation Site
|
T135K |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
E2 |
|
Combined Mutation
|
e2.D25N+e2.T135K+e2.R165Q+e2.I210T+e2.E232K+e2.T310K+e2.D344E |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
24150786
|
|
Disease
|
High grade squamous intraepithelial lesion;
Low grade squamous intraepithelial lesion;
Cervical carcinoma
|
|
Published Year
|
2014 |
|
Journal
|
Journal of medical virology |
|
Title
|
Functional effects of sequence variations in the E6 and E2 genes of human papillomavirus 16 European and Asian variants. |
|
Author
|
Hang D,Gao L,Sun M,Liu Y,Ke Y |
|
Evidence
|
There are seven amino acid substitutions between EUR E2 and As E2, including D25N, T135K, R165Q, I210T, E232K, T310K, and D344E.
|
|
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HPV Mutation Detail Information