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Mutation Information
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Mutation Site
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T1323C |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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X Promoter |
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Genotype/Subtype
|
C |
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Country
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China |
Literature Information
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PubMed PMID
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22919746
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Disease
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Chronic hepatitis B;
Liver cirrhosis;
Hepatocellular carcinoma
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Published Year
|
2012 |
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Journal
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Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology |
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Title
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[Hepatitis B virus (HBV) mutation in enhancer I (HBV Enh I)/X-promoter and the relationship between chronic HBV-related disease spectrum]. |
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Author
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Deng HH,Guan YJ,Lei CL,Xu M,Hu FY,Cheng J,Li YP |
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Evidence
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In the patients were infected with HBV genotype B, A1123Y mutation in LC was significantly higher than in CHB (30.56% vs. 8.58%, chi2 = 8.533, P = 0.005, A = 4.693, 95% CI [1.567-14.056]), HCC was significantly higher than in CHB (28.85% vs. 8.58%, chi2 = 8.607, P = 0.003, A = 4.324,95% CI [1.544-2.109])
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HBV Mutation Detail Information