HBV Mutation Detail Information

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Mutation Information
Mutation Site T131N
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype D
Country Italy
Literature Information
PubMed PMID 25418031
Disease HBV infection
Published Year 2015
Journal Hepatology (Baltimore, Md.)
Title Hepatitis B surface antigen genetic elements critical for immune escape correlate with hepatitis B virus reactivation upon immunosuppression.
Author Salpini R,Colagrossi L,Bellocchi MC,Surdo M,Becker C,Alteri C,Aragri M,Ricciardi A,Armenia D,Pollicita M,Di Santo F,Carioti L,Louzoun Y,Mastroianni CM,Lichtner M,Paoloni M,Esposito M,D'Amore C,Marrone A,Marignani M,Sarrecchia C,Sarmati L,Andreoni M,Angelico M,Verheyen J,Perno CF,Svicher V
Evidence Conversely, all the NLG sites (except the pattern,S113N1T131N) determined a drastic reduction in the quantification of the strep-tagged HBsAg when the Architect and Bio-Rad assays (both targeting the HBsAg) were used (Fig. 3).

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Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation