|
Mutation Information
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Mutation Site
|
T131N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
23180290
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
Virologica Sinica |
|
Title
|
A case of hepatitis B reactivation due to the hepatitis B virus escape mutant in a patient undergoing chemotherapy. |
|
Author
|
Wu C,Shi H,Wang Y,Lu M,Xu Y,Chen X |
|
Evidence
|
Before seroconversion of anti-HBs, the sequence analysis of the small HBsAg protein revealed HBV genotype C (HBsAg subtype adw) with several remarkable amino acid substitutions (F8L, S34L, F41S, G44V, F93C, V96G, L110I, T131N, C149Y and F161Y), mostly outside the “a” determinant (Fig. 2).
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HBV Mutation Detail Information