|
Mutation Information
|
Mutation Site
|
T131N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
AF286594
|
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
15953865
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2005 |
|
Journal
|
Journal of Korean medical science |
|
Title
|
Overlapping gene mutations of hepatitis B virus in a chronic hepatitis B patient with hepatitis B surface antigen loss during lamivudine therapy. |
|
Author
|
Lee SY,Choi MS,Lee D,Lee JH,Koh KC,Paik SW,Yoo BC |
|
Evidence
|
Sequencing of the 'a' determinant revealed amino acid substitutions as I126S, T131N, M133T, and S136Y.
|
|
|
HBV Mutation Detail Information