HBV Mutation Detail Information

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Mutation Information

Mutation Site	T127P
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Relevant Drug	hepatitis B immunoglobulin (HBIG)
Country	Turkey

Literature Information

PubMed PMID	31130119
Disease	Chronic hepatitis B
Published Year	2019
Journal	Mikrobiyoloji bulteni
Title	[HBV pol/S gene mutations in chronic hepatitis B patients receiving nucleoside/nucleotide analogues treatment].
Author	Kırdar S,Yaşa MH,Sayan M,Aydın N
Evidence	Because of the HBV pol/S gene overlapping, in 27 patients immun-selected amino acid substitutions (sI110L, sT127P, sS114A, sT123A), in nine patients HBIg selected escape mutants (sP120R, sT123N, sE164D, sY134F, sQ129H, sT118A, sP127K), in seven patients vaccine escape mutants (sT126I, sP120S, sG145A, s S193L) and in one patient misdiagnosis of HBsAg (sT131I) were detected.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation