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Mutation Information
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Mutation Site
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T127L |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
S |
Literature Information
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PubMed PMID
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20412171
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Disease
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HBV infection
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Published Year
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2010 |
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Journal
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Vox sanguinis |
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Title
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Performance evaluation of 70 hepatitis B virus (HBV) surface antigen (HBsAg) assays from around the world by a geographically diverse panel with an array of HBV genotypes and HBsAg subtypes. |
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Author
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Scheiblauer H,El-Nageh M,Diaz S,Nick S,Zeichhardt H,Grunert HP,Prince A |
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Evidence
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Genotypes/subtypes D/ayw3, E/ayw4, and F/adw4, which were detected with reduced sensitivity in some assays, share a substitution at position 127, i.e., P127T for the ayw3 subtype and T127I/L specific for E/ayw4 and F/adw4.
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HBV Mutation Detail Information