HBV Mutation Detail Information

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Mutation Information

Mutation Site	T126I
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Genotype/Subtype	D
Immune Escape	Y
Country	Caucasian

Literature Information

PubMed PMID	31542053
Disease	HBV-HCV coinfection
Published Year	2019
Journal	Journal of medical case reports
Title	Hepatitis B virus reactivation sustained by a hepatitis B virus surface antigen immune-escape mutant isolate in a patient who was hepatitis B core antibody positive during treatment with sofosbuvir and velpatasvir for hepatitis C virus infection: a case report.
Author	Foroghi Biland L,Ferrari L,Malagnino V,Teti E,Cerva C,Gentile A,Aragri M,Salpini R,Svicher V,Andreoni M,Sarmati L
Evidence	Sequencing analysis revealed the hepatitis B virus genotype D3 and the presence of two relevant immune-escape mutations (P120S and T126I) in the major hydrophilic region by analyzing the S region.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation