Mutation Information
Mutation Site
|
T126A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Country
|
China |
Literature Information
PubMed PMID
|
29629487
|
Disease
|
HBV infection
|
Published Year
|
2018 |
Journal
|
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology |
Title
|
Quasispecies characters of hepatitis B virus in immunoprophylaxis failure infants. |
Author
|
Wang X,Deng W,Qian K,Deng H,Huang Y,Tu Z,Huang A,Long Q |
Evidence
|
In our data, the substitution rate of amino acid located at a determinant is relatively low (< 10%), I/T126A, C124S, F134Y, K141Q, Q129H, D144A, G145V, and N146K, which showed no statistical difference to their mothers, proving that these vaccine escape mutants preexist maternally as minor variants.
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