HIV Mutation Detail Information

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Mutation Information

Mutation Site	T125F
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	NRTIs
Country	Brazil

Literature Information

PubMed PMID	30016324
Disease	HIV infection/AIDS
Published Year	2018
Journal	PloS one
Title	HIV-1 infection among crack cocaine users in a region far from the epicenter of the HIV epidemic in Brazil: Prevalence and molecular characteristics.
Author	França DDDS,Del-Rios NHA,Carneiro MADS,Guimarães RA,Caetano KAA,Reis MNDG,Martins RMB,Motta-Castro ARC,Stefani MMA,Teles SA
Evidence	Isolates from two participants showed mutations associated with resistance to nucleoside reverse transcriptase inhibitors (NRTI) only (M41L, T125C, T125F, M184V), while an isolate from one patient who had received antiretroviral therapy (ART) since 2008 had a mutation associated with resistance to non-NRTI (G190S).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation