|
Mutation Information
|
Mutation Site
|
T118V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.A128V+s.T118V |
|
Genotype/Subtype
|
D |
|
Country
|
Brazil |
Literature Information
|
PubMed PMID
|
18036224
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
BMC microbiology |
|
Title
|
Hepatitis B virus genotypes circulating in Brazil: molecular characterization of genotype F isolates. |
|
Author
|
Mello FC,Souto FJ,Nabuco LC,Villela-Nogueira CA,Coelho HS,Franz HC,Saraiva JC,Virgolino HA,Motta-Castro AR,Melo MM,Martins RM,Gomes SA |
|
Evidence
|
Three HBV genotype A isolates (358-S; 312-SE; 161-CW) were shown to harbor tyrosine to cysteine substitutions in determinant a residue 100 (Y100C), and the T118V-A128V double mutant was found in three genotype D isolates (Table 2).
|
|
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HBV Mutation Detail Information