|
Mutation Information
|
Mutation Site
|
T116N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
Literature Information
|
PubMed PMID
|
9728561
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
1998 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Emergence of an S gene mutant during thymosin alpha1 therapy in a patient with chronic hepatitis B. |
|
Author
|
Tang JH,Yeh CT,Chen TC,Hsieh SY,Chu CM,Liaw YF |
|
Evidence
|
Sequence analysis revealed an S gene mutant in HBsAg-seronegative serum with two consecutive amino acid substitutions: threonine115-to-isoleucine and threonine116-to-asparagine, whereas no amino acid substitution or deletion was found in the pre-S region.
|
|
|
HBV Mutation Detail Information