HBV Mutation Detail Information

> T116N Search Result


Mutation Information
Mutation Site T116N
Mutation Type Amino acid level
Gene/Protein/Region Type S
Viral Reference AB697502; AB246345; JQ801515; AB246346; JQ801516; AB246339; AB900105; AB246342
Immune Escape Y
Country Japan
Literature Information
PubMed PMID 30584239
Disease HBV infection
Published Year 2018
Journal Scientific reports
Title Expansion of viral variants associated with immune escape and impaired virion secretion in patients with HBV reactivation after resolved infection.
Author Inuzuka T,Ueda Y,Arasawa S,Takeda H,Matsumoto T,Osaki Y,Uemoto S,Seno H,Marusawa H
Evidence Moreover, three patients in the non-HSCT group had predominant variants with sT116N, sT123N, and sG130N changes, which resulted in the addition of NLG sites by substitutions of threonine or glycine with asparagine.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation