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Mutation Information
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Mutation Site
|
T116N |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.S132Y+s.T116N+s.S114K |
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Genotype/Subtype
|
B |
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Viral Reference
|
AB033556;
D00330 |
|
Country
|
China |
Literature Information
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PubMed PMID
|
28600703
|
|
Disease
|
Chronic hepatitis B
|
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Published Year
|
2017 |
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Journal
|
Archives of virology |
|
Title
|
Prevalence of S gene mutations within the major hydrophilic region of hepatitis B virus in patients in Dongguan, southern China. |
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Author
|
Li S,Xie M,Li W,Peng Q,Zhong B,Lu X,Ma Q |
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Evidence
|
In genotype B strains, sY100C/Q129R/G145A, sY100C/E164G, sY100S/M133L, sM103I/T123A, sS114K/T116N/S132Y, sP120T/M133L, sP120S/K160N, sP120T/A157G, sP120Q/T126A, sK122I/P127T/G130N and sD144A/A157G were found (Fig. 1). In genotype C isolates, sY100C/Q101K, sY100C/I126N/M133T, sL104F/ G145R, sL109P/A128V/Q129K, sS114A/G145A, sG130K/A166G, sT131N/Q101K/I126S/M133T, sT131N/sM133T/F134L and sM133S/G145A and sT131N/M133S were found (Fig. 1).
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HBV Mutation Detail Information