|
Mutation Information
|
Mutation Site
|
T1134C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
LMP2 |
|
Viral Reference
|
NC_007605.1;
DQ279927.1;
V01555.2;
AY961628.3;
HQ020558.1;
JQ009376.2 |
|
Country
|
Beijing; China |
Literature Information
|
PubMed PMID
|
27189712
|
|
Disease
|
Lung carcinoma
|
|
Published Year
|
2016 |
|
Journal
|
Scientific reports |
|
Title
|
Identification and Characterization of Epstein-Barr Virus Genomes in Lung Carcinoma Biopsy Samples by Next-Generation Sequencing Technology. |
|
Author
|
Wang S,Xiong H,Yan S,Wu N,Lu Z |
|
Evidence
|
A T-to-C substitution at 1134 resulted in the change of residue 251 (I-to-T) in LMP2, where CD8+ epitopes TVC and MFI were located. A T-to-C substitution at 84175 resulted in the change of residue 399 (A-to-P) in EBNA3B protein, where HLA A11-restricted immunodominant epitope AVF was locate.
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EBV Mutation Detail Information