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Mutation Information
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Mutation Site
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T109M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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C |
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Genotype/Subtype
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D |
Literature Information
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PubMed PMID
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30089690
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Published Year
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2018 |
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Journal
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Journal of virology |
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Title
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Assembly Properties of Hepatitis B Virus Core Protein Mutants Correlate with Their Resistance to Assembly-Directed Antivirals. |
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Author
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Ruan L,Hadden JA,Zlotnick A |
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Evidence
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We examined the effects of two closely related CpAMs, HAP12 and HAP13, which differ by a single atom but have drastically different antiviral activities, on the assembly of wild-type Cp and three T109 mutants (T109M, T109I, and T109S) that display a range of resistances.
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HBV Mutation Detail Information